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Regis O'Keefe

American Orthopaedic Association


Regis J. O’Keefe is the Fred C. Reynolds Professor and Chair, Department of Orthopaedic Surgery at Washington University School of Medicine in St. Louis, Missouri. Dr O’Keefe graduated magna cum laude at Yale University. After earning his medical degree at Harvard Medical School, he completed a Ph.D. in biochemistry and biophysics from the University of Rochester School of Medicine and Dentistry. Dr O’Keefe served his internship in surgery at New England Deaconess Hospital in Boston, his residency in orthopaedics at the University of Rochester Medical Center and completed an oncology fellowship at the Massachusetts General Hospital. He previously served as the Marjorie Strong Wehle Professor and Chair, Department of Orthopaedics and Rehabilitation and Associate Dean of Clinical Affairs at the University of Rochester School of Medicine and Dentistry.


Dr O’Keefe has authored numerous articles, book chapters and reviews concerning bone repair and development, cancer, inflammatory diseases of bone, genetics, and related topics, and in 2014 received the ORS/OREF Distinguished Investigator Award for lifetime contributions to the field of musculoskeletal research.


Dr O’Keefe is a past-President of the Orthopaedic Research Society (ORS) and is a member of the Board of Directors of the American Board of Orthopaedic Surgery (ABOS). He has served as the Secretary of the Orthopaedic Research and Education Foundation and is the past-President of the United States Bone and Joint Decade.


Dr O’Keefe has served as the Chair of the American Academy of Orthopaedic Surgeons’

Clinician Scientist Committee where he initiated the AAOS/ORS/OREF Clinician Scientist

Development Program. He is a former ABC Travelling Fellow and served as chair of the Critical Issues Committee prior to joining the A(m)OA presidential line.